| The Human Genome Project Video - 3D Animation Introduction |
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Human Genome Project; An introduction to the
ongoing Human Genome Project. The dynamic 3D
animation will take you "inside" for a close
up look at the complexity of the cell.
Completed in 2003, the Human Genome Project
(HGP) was a 13-year project coordinated by
the U.S. Department of Energy and the
National Institutes of Health. During the
early years of the HGP, the Wellcome Trust
(U.K.) became a major partner; additional
contributions came from Japan, France,
Germany, China, and others. See our history
page for more information. Project goals were
to identify all the approximately
20,000-25,000 genes in human DNA, determine
the sequences of the 3 billion chemical base
pairs that make up human DNA, store this
information in databases, improve tools for
data analysis, transfer related technologies
to the private sector, and address the
ethical, legal, and social issues (ELSI) that
may arise from the project. Though the HGP is
finished, analyses of the data will continue
for many years. Follow this ongoing research
on our Progress page. An important feature of
the HGP project was the federal government's
long-standing dedication to the transfer of
technology to the private sector. By
licensing technologies to private companies
and awarding grants for innovative research,
the project catalyzed the multibillion-dollar
U.S. biotechnology industry and fostered the
development of new medical applications.
Knowledge about the effects of DNA variations
among individuals can lead to revolutionary
new ways to diagnose, treat, and someday
prevent the thousands of disorders that
affect us. Besides providing clues to
understanding human biology, learning about
nonhuman organisms' DNA sequences can lead to
an understanding of their natural
capabilities that can be applied toward
solving challenges in health care,
agriculture, energy production, environmental
remediation, and carbon sequestration. A
genome is all the DNA in an organism,
including its genes. Genes carry information
for making all the proteins required by all
organisms. These proteins determine, among
other things, how the organism looks, how
well its body metabolizes food or fights
infection, and sometimes even how it behaves.
DNA is made up of four similar chemicals
(called bases and abbreviated A, T, C, and G)
that are repeated millions or billions of
times throughout a genome. The human genome,
for example, has 3 billion pairs of bases.
The particular order of As, Ts, Cs, and Gs is
extremely important. The order underlies all
of life's diversity, even dictating whether
an organism is human or another species such
as yeast, rice, or fruit fly, all of which
have their own genomes and are themselves the
focus of genome projects. Because all
organisms are related through similarities in
DNA sequences, insights gained from nonhuman
genomes often lead to new knowledge about
human biology. Producer: NIH
Contact Information:
http://www.genome.gov/Pages/EducationKit/
Creative Commons license:
Attribution-NonCommercial-NoDerivs
Tags : Human Genome Project genetics genes research education DNA cell chromosomes nucleus proteins RNA biotechnology biology |
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Affichage : 65993
Durée : 213 s |
| Aging of the Other Genome: A Decisive but Ambitious Solution |
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Google Tech Talks
December, 19 2007
The DNA in our cells consists of not only the
well-known 46
chromosomes currently receiving such avid
attention from specialists
in sequencing technology, but also a large
number of copies of a
relatively tiny, circular DNA molecule inside
the "powerhouse of the
cell," the mitochondrion. Among other
things, mitochondria perform
the chemistry of breathing - they extract
energy from nutrients by
exquisitely regulated chemical reactions that
consume oxygen and
create CO2. This vital function depends on
the 13 proteins encoded by
the mitochondrial DNA (mtDNA), as well as on
hundreds of proteins
that are encoded in our more famous genome
and imported across the
mitochondrial surface after construction in
the body of the cell. The
mtDNA accumulates mutant, non-functional
variants far faster than our
main genome, so 20 years ago scientists began
looking at the idea of
putting copies of the 13 genes of interest
into the nucleus after
making modifications that would cause them to
be processed by the
same "protein import" machinery that
processes the mitochondrion's
many other proteins, thus making the mtDNA
itself superfluous and
mutations in it harmless. I will discuss this
concept in detail in my
talk. Progress has been very erratic in the
meantime but is now very
rapid, partly because of Methuselah
Foundation-funded research.
However, this approach may still prove
impossible, so many other,
ostensibly simpler ideas - some more
promising than others - have
been proposed, and I will describe some of
these too.
Speaker: Dr Aubrey de Grey
Aubrey de Grey is a biomedical gerontologist
based in Cambridge, UK,
and is the Chairman and Chief Science Officer
of the Methuselah
Foundation, a 501(c)(3) non-profit charity
dedicated to combating the
aging process. He is also Editor-in-Chief of
"Rejuvenation Research",
the world's only peer-reviewed journal
focused on intervention in
aging. His research interests encompass the
etiology of all the
accumulating and eventually pathogenic
molecular and cellular
side-effects of metabolism ("damage") that
constitute mammalian aging
and the design of interventions to repair
and/or obviate that damage.
He has developed a possibly comprehensive
plan for such repair, termed
Strategies for Engineered Negligible
Senescence (SENS), which breaks the
aging problem down into seven major classes
of damage and identifies
detailed approaches to addressing each one. A
key aspect of SENS is
that it can potentially extend healthy
lifespan without limit, even
though these repair processes will never be
perfect, as the repair only
needs to approach perfection rapidly enough
to keep the overall level
of damage below pathogenic levels. de Grey
has termed this required
rate of improvement of repair therapies
"longevity escape velocity".
Tags : google techtalks techtalk engedu talk talks googletechtalks education |
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Affichage : 16109
Durée : 3746 s |
| How Big is Your Genome? Strange DNA |
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How Big is Your Genome
Strange DNA Facts
This video discusses some strange facts about
DNA, genes, genetics and the human genome.
How large is the human genome?
How does the human genome compare to a
PlayStation 3.
Is there such a thing as a gay gene?
How are the different human races different
genetically?
Are mental disorders causes by genetics?
How large is the human genome compared to a
mouse or a grain of rice?
Crystal is graduated from Texas A&M
University w/ a degree in agricultural
leadership and development with an emphasis
on genetics and bio-chemistry. She is
currently a professional model.
Visit Crystal's Website
http://www.crystalnichole.com/
This video was produced by Psychetruth
http://www.myspace.com/psychtruth
http://www.youtube.com/psychetruth
http://www.livevideo.com/psychetrut
© Copyright 2007 Zoe Sofia. All Rights
Reserved.
Tags : Strange DNA genes genetics evaluation mental health disorder science adhd gay dawkins model size psychiatry hot illness |
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Affichage : 27477
Durée : 579 s |
| Genome Music |
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The day (in 2001) the genome sequence became
available, Todd Barton 'sonofied' the
sequence. Todd is the music director of the
Oregon Shakespeare Festival. Hear & learn
more at ToddBarton.com.
Tags : genome music Todd Barton dna rna gene |
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Affichage : 1185
Durée : 599 s |
| Charlie Rose - HUMAN GENOME SPECIAL PART 5 |
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Dr. Henry Kissinger, Former Secretary of
State (from 12/27/99); Dr. Hamilton Smith,
Nobel Laureate / Celera Genomics; Dr. Harold
Varmus, President & CEO, Memorial
Sloan-Kettering Cancer Center; Dr. Arnold
Levine, President, Rockefeller University;
Dr. James Watson, President, Cold Spring
Harbor Laboratory; Dr. William Haseltine, CEO
& Chairman, Human Genome Sciences, Inc.; Dr.
Arthur Caplan, Director, Center for
Bioethics, UPENN; Dr. Craig Venter, Chairman
& Chief Scientific Officer, Celera Genomics;
Dr. Francis Collins, Director, National Human
Genome Research Institute
Tags : charlie_rose tvshow charlie_rose_archive |
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Affichage : 1116
Durée : 3531 s |
| Keeping Up With The Human Genome |
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Google Tech Talks
December 1, 2006
ABSTRACT
The Human Genome Sequence was a big jump in
scale for the then young bioinformatics
field. Thirty times bigger than the worm
genome that we were only just getting to
grips with and with far greater numbers of
interested users. The Ensembl project was
started from scratch to handle this data: a
system to store the data in an RDBMS; a
pipeline to generate a pre-computed set of
analysis; an API to provide both web and
programmatic access. Ensembl evolves
continuously: a new release is made every 2
months and in nearly every release the schema
is updated to handle new data types. It now
integrates more than thirty large genomes and
provides researchers with...
Tags : google howto keeping human genome |
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Affichage : 1002
Durée : 2242 s |
| The Human Genome: Human Genetics and the Brain |
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Dr. Louis Ptacek's research focuses on
identification and characterization of genes
that cause normal variations and disorders of
the nervous system. Series: "UCSF Mini
Medical School for the Public" [7/2006]
[Health and Medicine] [Show ID: 11682]
Tags : health human genetics brain |
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Affichage : 1894
Durée : 3573 s |
| Pimp my Genome! The Mainstreaming of Digital Genetic... |
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Google Tech Talks
May 3, 2007
ABSTRACT
DNA is a programming language for living
cells. The cell's basic operating system, or
genome, directs functions like growth and
reproduction, energy utilization, and the
production of useful compounds like ethanol
or penicillin. With genetic engineering, new
functions can be added to cells or broken
metabolic pathways repaired. Until recently,
genetic engineering has required the DNA
molecule itself to be physically manipulated,
a tedious and expensive process. Now,
automatic DNA synthesis permits virtually any
DNA code to be made from scratch, opening up
genetic engineering to anyone with a computer
and a credit card. The capabilities of this
new synthetic...
Tags : google howto pimp genome mainstreaming |
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Affichage : 1979
Durée : 3581 s |
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